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PATCHED RECEPTORS
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DeCS
Descriptor
English
:
Patched Receptors
Descriptor
Spanish
:
Receptores Patched
Descriptor
Portuguese
:
Receptores Patched
Synonyms
English
:
Patched Protein
Patched Receptor
Patched Sonic Hedgehog Receptors
Receptor, Patched
Receptors, Patched
Tree Number:
D12.776.543.750.058
D12.776.624.776.633
Definition
English
:
A
family
of 12-pass transmembrane
proteins
originally identified in
Drosophila
that are receptors for
HEDGEHOG PROTEINS
. They have important roles in regulating
CELL PROLIFERATION
; CELL DIFFERENTIAION; and
BODY PATTERNING
and may also function as
TUMOR SUPPRESSOR PROTEINS.
History Note
English
:
2017 (1996)
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
56640
Unique Identifier:
D000072079
Occurrence in VHL
:
Similar:
DeCS